Hades Keepsakes Guide
Keepsakes are items that you can equip for buffs during an escape attempt. You acquire them by gifting characters with Nectar. When given their first Nectar, the character will reward you with their Keepsake. Hades is the exception; his keepsake does not come until you complete the normal ending so do not waste any of your Nectars on him early on.
Keepsakes can be equipped in the display case in the courtyard besides your weapons. Once a keepsake is equipped, it cannot be removed, only exchanged for a different one.
Keepsakes can be changed mid-run if you have bought the Keepsake Collection, Regional upgrade from the House Contractor. In the room after each boss you’ll find the Keepsake Collection. Switching keepsakes and closing the collection will lock you into using this keepsake until the next collection point. If you close the collection without changing keepsakes you can still open the collection to change it. This plays an important role in longer runs as some keepsakes provide most benefit at the start and others are more useful later on.
FYI, this is not a list of all keepsakes, but a list of some useful general keepsakes to start a fresh run off with.
Another type of keepsake that is useful for runs are the God ones. They provide ‘The next Boon you find will be from [God], +10/15/20% chance to be Rare or better.’ These are excellent for getting a particular God for a build you want. Some Gods are much better for some weapons than others. The other keepsakes are good, general keepsakes, God keepsakes are best used at start of runs to get the build you want, then switched out after first boss for a good general keepsake. Give Nectar to the Gods whose playstyle fits with your favourite weapons most..